Rhinologic signs associated with snuff taking

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Snuff-induced carcinogenesis: effect of snuff in rats initiated with 4-nitroquinoline N-oxide.

A canal in the lower lip to function as a reservoir for snuff was surgically created in 150 male Sprague-Dawley rats. The animals were randomized into five groups of 30 each: Group I received snuff twice a day, 5 days a wk; Group II was painted with propylene glycol (solvent control) on the hard palate 3 times a wk during 4 wk; Group III underwent painting on the hard palate with 4-nitroquinoli...

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ژورنال

عنوان ژورنال: European Annals of Otorhinolaryngology, Head and Neck Diseases

سال: 2020

ISSN: 1879-7296

DOI: 10.1016/j.anorl.2019.10.002